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The applied constraints were between 0.1 and 10 mm, equally distributed on a logarithmic scale.
The MGP results are however strongly dependent on the starting conditions and the applied constraints.
In the optimization process, the applied constraints are voltages of nodes, currents of branches, and radial condition of the network.
In this report we study this dependence by investigating different starting pupil functions and introducing modifications to the applied constraints.
The current study shows that derivation of sustainable yield using conservation of mass principles leads to expressions for basin sustainable that can be readily determined using numerical modeling methods and selected on the basis of applied constraints.
Optimal concentration of chitosan (A) and TPP (B) were found 0.6 mg/mL and 0.4 mg/mL with 120 min stirring time (C), with applied constraints of minimizing particle size (R1) and maximizing encapsulation efficiency (R2) and drug release (R3).
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These values supported the applied constraint of a missing carboxylating anaplerotic reaction from pyruvate towards oxaloacetate.
"They tend to apply constraints that are more difficult to implement".
This method can apply constraints of fault parameters as prior information.
Typically, the isotropy is enforced by applying constraints to the optimization problem.
λ V × S CV + λ I × S CI is used to apply constraints on the objective function.
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