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We also excluded rotational atherectomy and brachytherapy from the main network and applied a study size filter of at least 50 patients per arm in the attempt to minimise possible influences of outdated treatments and smaller trials.
The following inclusive selection criteria were applied: (a) study design: RCT; (b) study population: adult critically ill patients receiving mechanical ventilation; (c) intervention: oral care with toothbrushing (regardless of approach and liquid applied); (d) comparison intervention: oral care without toothbrushing; and (e) outcome measure: the incidence of VAP.
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We applied a single blind study.
Both datasets apply a study design that includes multiple doses and treatment durations across different assay systems.
By contrast, Korean studies largely applied a descriptive study design, and few qualitative studies have been performed.
Thus we applied a complementary study with geologists that teach biology in the education.
Nine studies applied a randomized controlled study design, three a controlled design only.
The study applies a case study design.
This study applied a cross-sectional survey design.
Specifically, we applied an event-study approach within a time window of 7 days before and after each entry.
Future studies are needed to confirm our findings in larger patient cohorts possibly by applying a prospective study design.
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