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The participants in our study were almost 90% white, so our conclusions might be limited in their application to other populations.
In addition, while our questionnaire categories demonstrated excellent internal consistency, as evidenced by high Cronbach's α values, further validation techniques would be needed before application to other populations.
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However, as more data on vaccine impacts on IMD incidence and serogroup prevalence become available over time, such new data can be used to further validate dynamic models, which can then be used to evaluate potential expansions of vaccine programs, or applications to other populations that do not currently have vaccine programs.
However this protocol may have a broader application to other clinical populations with suboptimal bone mass, as well as military recruits, and athletic populations such as gymnasts and runners that are susceptible to fatigue-type stress fractures in the foot [ 27].
Our results have several limitations for clinical application to other ICU populations.
Our results might be influenced by the underlying trauma mechanisms and, therefore, its application to other trauma populations might be limited.
However, application of this method to other populations is limited because of dissimilar sources, meteorologic conditions, and other social and cultural factors.
While VICUNA was developed for the analysis of viral populations, its application to other heterogeneous sequence data sets such as metagenomic or tumor cell population samples may prove beneficial in these fields of research.
The PMRP biospecimens are overwhelmingly Caucasian therefore this is appropriate for our application, however this emphasis may decrease the applicability of this assay to other populations.
The success of the D R mathematical model suggests that it may have broader application to other viral infections among the human population in China and may be modified for application to other regions of the world.
Its value is in the application to other processes".
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