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Regarding the 3rd step, anti-CD4 antibody application suppressed CD4+ T cell accumulation and EAE-relapse but not somatosensory activations, sympathetic activations, or MHC class II+CD11b+ cell accumulation in the ventral vessels, suggesting that CD4+ T cell accumulation is a downstream event of sensory and sympathetic activation and of MHC class II+CD11b+ cell accumulation in the ventral vessels.
Publicly available DNA array expression data (Geoprofiles, GDS2324) (Coser et al, 2003) had already indicated a tight co-regulation of Mb and ER α mRNAs in the breast cancer cell line MCF7 by showing that oestrogen starvation was able to induce, while oestrogen application suppressed, Mb and ER α transcripts in either a time- or dose-dependent manner (Supplementary Figure S5; ER α=ESR1 in figure).
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NPY is found in pancreatic islets [7], [8] and its exogenous application suppresses insulin release from perfused islets [9].
Because muscimol application suppresses the spike activity of cortical neurons leaving transmitter release intact at geniculocortical synapses, local synaptic interaction may underlie the retraction of active axons in the inhibited cortex.
Several studies also report that vermicompost application suppresses infection by insect pests, repel crop pests and induce biological resistance in plants against pests and diseases due the presence of antibiotics and actinomycetes (Munroe 2007).
As indicated by the absence of signal in T3 legs from early to late embryogenesis (Figs. 4D and 4F), the RNAi application suppresses Ubx expression throughout cricket development.
In ABA-deficient tomato and maize ABA-biosynthesis mutants, exogenous ABA application suppresses ethylene production [ 41, 52, 53].
TSA application alone suppressed root elongation (Fig. 9b).
Sucrose application partially suppressed the delay in the juvenile-to-adult phase transition caused by defoliation.
In the present study, increased MPO activity both in the systemic circulation and in the lungs due to S/C application was suppressed by EP.
DIDS and DCPIB application significantly suppressed tunicamycin-induced upregulation of chaperone protein GRP78 and the transcriptional factor ATF4, and downregulation of XBP1S.
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