Sentence examples for application of trial from inspiring English sources

This article reviews the statistical differences between superiority, equivalence, and noninferiority design schemes, which pose specific ethical questions and have important implications for interpretation and clinical application of trial results.

There has lately been a growing level of interest in assessing the quality of clinical trials, not only with regard to internal validity, but also in terms of a host of parameters that might guide the application of trial results to informing decisions about the development of medical products, medical practice, or health policy.

Hence application of trial based predictions of treatment effect to the general population may be suboptimal.

As in all models, limitations occur due to application of trial findings to real-world clinical practice, data assumptions, and structural choices.

In this common situation, observational studies provide useful information for application of trial results to clinical practice (Vijan et al, 2000).

Thus one might imagine that legal suits could arise from the application of trial methodology or clinical practice that does not meet international standards.

20 21 Another useful application of clinical trial registration is that registered clinical trial data are increasingly being used to shed light on what clinical trial research is being conducted, where it is being conducted, by whom and how.

Experience of working in clinical trials (which could be as a recruiter, a Trial Manager, a reviewer of ethical applications of trials) ranged from 3 to 20 years.

Secondly, ours was a pragmatic trial, and we were broad and inclusive in the application of our trial inclusion criteria.

Clinical trial designs must be relevant to the whole population with the disease, not just the trial population, and the clinical indications for new drugs should not be limited by slavish application of restrictive trial entry criteria when the results are applied to the population.

Understanding GA progression and its individual variability is critical in the design of clinical studies, in the interpretation and application of clinical trial results, and for counseling patients on how disease progression may affect their individual prognosis.