Sentence examples for application of the virus from inspiring English sources

This information was then used to inform an infection model to test the application of the virus in two urban environments: Belfast, Northern Ireland and London, England, with data extracted from Wigle.net.net

As a possible solution to this limitation, intravenous (iv) application of the virus was investigated in subsequent studies in mice with established subcutaneous xenograft tumours derived from a series of human tumour cell lines, i.v. injection of ONYX-015 caused significant growth inhibition and increased survival in all cases (Heise et al, 1999b).

In light of the poor capacity of SFV to replicate in dogs upon intravenous injection, clinical application of the virus in canine cancer patients would most likely entail intratumoral virus injections ensuring successful delivery of the virus into the tumor mass.

We discuss the potential application of these viruses in biomedicine in relation to their complement activating properties.

However, application of this virus-mediated direct conversion is still limited due to concerns on clinical safety.

Different dosing schedules were tested and showed that virus application for five consecutive days was superior to a one-time application of the same total virus dose (Heise et al, 1999a).

The experimental design consisted two modes of application, such as exposure of the virus to the extract and injection challenge, and oral administration of the extract coated feed followed by oral challenge.

Thus the transmission pathways of norovirus are complex and the application of molecular typing of the virus holds promise in furthering understanding of transmission [ 5]/ Molecular data have been used to describe the genetic diversity of norovirus in various national and regional populations [ 6- 14].

However, an inherent characteristic of recombinant Ad for gene therapy applications is the ability of the virus to elicit a strong immune response even in immunocompetent hosts, making Ad-based vectors attractive vaccine carriers [8].

As such, the application of viruses such as Newcastle disease virus (NDV) as a novel biological bullet to specifically target aberrant signalling in GBM has brought new hope.

This chapter will review the recent clinical application of therapeutic viruses for the treatment of cancer.