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Participants also expressed that 10 mm was a high threshold in terms of useful application of the map.
Finally, note that all solutions with initial conditions on the positive x-axis enter the region ( 0, ∞ ) 2 under a single application of the map T. The proof of the case α 1 ≠ 0 and α 2 = 0 in (11) is similar to the previous case and we skip it.
One application of the map could be to determine the likely affect of targeting specific genes in the map, and to understand the effect that different drugs (that target nodes in the map) have on the rest of the network.
It can also be argued that map distance estimates are less important than marker order, as map distances do vary between different genetic linkage maps by several centimorgans [ 37], and that the marker order is the most critical feature for further application of the map, for example, for map-based cloning.
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The mapping is bijective, so reverse application of the mapping to a mapped nucleotide, returns the original nucleotide.
To avoid small time steps introduced by the transformation optics approach, an additional application of the mapping of the material matrix to a dispersive material model is employed.
For example, the valuation approach has been taken to determine the utility values of the health outcomes or states defined by the EQ-5D-3L questionnaire [ 2], and the availability of the EQ-5D-3L utility values in turn has stimulated the application of the mapping approach to many HRQoL instruments whose utility values are unknown [ 3].
We can divide the various applications of the map metaphor into two basic categories.
Note that application of the Kosambi mapping function changed the total map length from individual crosses by less than 1%.
Linkage analysis was performed and markers were assimilated into groups for mapping with the application of the Kosambi mapping function.
The return map is given by a further application of the firing map so that (R phi =h(h phi))).
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