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Intra molecular distance ranges are used as shape descriptors and are pre-calculated by the application of the alignment machinery itself in an initialization stage.
Possible application of the alignment and assembly free approach requires further exploration for other types of sequencing data, such as RAD-seq and metagenomic data especially for organisms without a reference.
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NetworkBLAST is an exhaustive approach and is limited in its application to the alignment of only up to three networks, while an extended version, NetworkBLAST-M, can handle multiple networks [ 34].
Figure 2 The realigned Dolphin after application of the coarse alignment.
The practical application of the canal alignment process using the topographic surveyed data or toposheet is also included in the chapter through worked example.
Application of the harmonic alignment algorithm after the hybrid algorithm further improved the suppression on the formant part (harmonic part) of the interference signal.
The reason is that the scheduler never generates a non-reasonable schedule due to the application of the greedy alignment procedure.
Overall, the application of the BWT alignment method as implemented in NextGENe led to a reduction in the number of discrepancies between the STS and PGM generated data in the HVS-2 and HVS-3C tracts and when considering substitutions across the genome (Table 1).
The application of the classic alignment-based algorithms (e.g. PCA, LDA, etc).
An application of the pairwise alignments is the synteny analysis of the structured RNA annotation in pig.
The different levels of conservation between these regions lead to a direct application of the syntenic global alignment to the gene prediction problem.
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