Sentence examples for application of targeted from inspiring English sources
Therefore, EC0746 is a classic example of the application of targeted drug delivery, in this case the targeting of the antifolate (AMT) to FR-β-carrying cells.
To date, conventional chemotherapy-based cancer treatment is increasingly seconded by the application of targeted therapeutics, for example, inhibitors of kinases, the proteasome or NF- κB activation, as well as drugs targeting apoptotic pathways, including Smac and BH3 mimetics and agonists of apoptosis-inducing TRAIL receptors.
Therefore, our data also emphasize that the practical application of targeted toxins in the clinic will require that we are successful in our efforts to make the tumor targeting as selective as possible and/or using delivery methods that are able to avoid susceptible normal tissues.
While Athens contends it is around €500m, and can be easily filled with the application of "targeted measures" and structural reforms, lenders say it is at least four times bigger and will require extra budget cuts to be resolved.
However, a large number of challenges should be considered and overcome during the development and clinical application of targeted agents.
Likewise, improved diagnostic measures are essential in guiding the application of targeted therapies and preventing the evolution of therapeutic resistance.
The application of targeting a NR with specific ligands was further demonstrated by V Balasubramaniyan (Institute of Hepatology, University College London, London, UK).
Towards a clinical application of targeting the B7-H3 pathwey, wexamineded the therapeutic efficacy of anti-B7-H3-blocking mAb in pancreatic cancer.
The above data support a pivotal role for COX-2 expression in tumors treated with irradiation and thus justify studies to evaluate the clinical application of targeting COX-2 in patients undergoing radiation therapy as a treatment for prostate cancer.
They have served as nanocarriers in applications of targeting drug delivery systems.
The article also outlines a few examples predicting other possible applications of targeting such specific probes not yet used.
