The phrase "application of substitution" is correct and usable in written English.
It can be used in contexts related to mathematics, programming, or any field where substitution is applied to variables or elements.
Example: "The application of substitution in solving equations can simplify complex problems significantly."
Alternatives: "use of substitution" or "implementation of substitution".
All other 1H- and 13C-resonances of all structures were finally assigned on the basis of comparison with literature data of structure related compounds and according to application of substitution additive rules of 13C NMR.
Furthermore, application of substitution rates from other taxa is not appropriate because the assumption of molecular clock in our data is violated.
On the other hand, our vast background knowledge regarding rRNA molecules offers a unique opportunity to study the effects of selection and application of substitution models in greater detail.
The data presented is the result of sustained applications of substitution mapping for over a decade and constitutes the first report of a BP QTL within a very short congenic segment, containing variants within a single rat gene, Adamts16.
The decomposition of a restricted process ({(mathbf{nu } a }p)—where (a in mathcal {L})—generates the multiset obtained from the decomposition of p, to which the substitution ({{a'/a}}) is applied; the application of the substitution ({{a'/a}}) to a multiset is performed elementwise, as shown in the example below.
Despite early claims of similar substitution rates among bacteria [ 5, 9] and the application of eukaryotic substitution rates to bacteria [ e.g., [ 33]], no single evolutionary rate can be applied across diverse bacterial lineages or over broad evolutionary periods.
An application of the substitution(theta ) to the expression (E) (namely, to a term or to a formula) results in the expression (Etheta ), which is obtained from (E) by replacing every occurrence of the variable (x_i) by the term (t_i).
Inferred site covariation patterns were used then to guide the application of mixed substitution models in subsequent phylogenetic analyses.
Application of RNA substitution models in phylogenetics is still confined to a few studies [ 11, 18- 27], most of them emphasing improvement of the analyses.
This problem could neither be solved by repeating runs with higher sample frequencies nor with the application of simpler substitution models, as proposed in Pepper et al.[ 13], and indicates that the species tree results must be treated with caution.
Note that, the application of a simple substitution ciphers to the items of the original database is not enough to protect privacy in this setting.
