Results from an earlier evaluation of the application of site-specific 99mTc-labeling of the Affibody molecule, ZHER2 2395-C, were favorable.
The results may broaden the application of site-specific recombination in basic and applied research, including the custom-design of recombinases for natural, asymmetric, and lox-related target sequences present in the genome.
Development of 99mTc agents will likely extend the application of site-specific brain radiopharmaceuticals for routine applications in aiding the diagnosis and monitoring treatments of various neurologic and psychiatric disorders.
To this end, we envisage the application of site-specific genome-editing techniques to be game-changing.
One attractive application of site-specific nucleases is genome editing in patient-derived induced pluripotent stem (iPS) cells for the development of personalized cell therapy against intractable human diseases (Urnov et al., 2010).
Application of the site and branch-site models detected positive selection on exon B (P<0.011) in the subgenus Drosophila during the diversification of D. grimshawi, D. mojavensis and D. virilis (Table 1).
The present review will highlight some of the potential applications of site-directed O-glycosylation.
Application of single-site laparoscopic colectomy to acute cecal volvulus is feasible using decompression of the dilated colon by inserting a catheter through the amputated appendix.
Glyco-engineering is an approach to facilitate the hyper-glycosylation of recombinant proteins by application of the site-directed mutagenesis methods.
