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This chapter discusses in detail the application of silk based scaffolds in engineering hard and soft neotissue as well as organ-specific tissue.
The application of silk on tissue engineering scaffolds has been studied intensively because silk has an electrospinning technique using a good blood compatibility, excellent cytocompatibility and biodegradability.
Research into the application of silk fibroin (SF) in tissue engineering has been increasing, though to date has not focused on dermal regeneration.
It will do so by reviewing silk properties, structure and formation, with special focus on spider and mulberry silkworm silk fibres, as well as the application of silk in the biomedical field.
Several studies published in the recent literature were concerned about the potential application of silk fibroin fibres derived from Bombyx mori silk.
Although the most appropriate model for studies of periodontal disease pathogenesis in experimental primates appears to involve the application of silk ligatures, some difficulties may occur in establishing periodontal tissue breakdown by using this model.
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These findings potentially broaden the application of silk-based ligamentous graft for ACL reconstruction and further large animal study.
Here, we review the current understanding of spider silk and its assembly process, as well as discuss the application of silk-based materials to the fields of biomedicine and materials engineering.
In this article progress made in the application of silk-elastinlike protein polymers (SELPs) as matrices for the delivery of drugs, genes, viral vectors, and recently tissue engineering is reviewed.
Aramwit, P., Siritientong, T. & Srichana, T. Potential applications of silk sericin, a natural protein from textile industry by-products.
Finally, there will be an account of previous biomedical applications of silk.
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