The amplification strategy performed good promise for clinical application of screening of cancer biomarkers.
Application of screening questions is also relevant, as differences would be expected when applying key questions such as, "Have you ever suffered from headache?" versus "Have you had a headache within the past year?", or "past three months", as in our study[30].
Unfortunately, we have no assurance that appropriate application of screening tools will guarantee the removal of all erroneous models in all circumstances.
Such results have implications on the practical application of screening, and on the public health policy.
Therefore, there is a need also to evaluate any routine application of screening services.
To ensure uniformity in the application of screening procedures, a training course for GPs on standardization of measurements was organized.
There is no effective way to prevent breast cancer which is why the appropriate application of screening mammography is critical.
The application of screening instruments like the SDQ can be meaningful, in the sense that children are screened before psychosocial problems exacerbate, only if they are used appropriately.
The application of screening technology incorporating digital rectal examination, measurement of PSA and use of transrectal ultrasonography has identified a huge reservoir of previously undetected cases.
Other limitations of the randomised controlled trials include the generalisability of results for the population as a whole and for application of screening in routine practice.
