Sentence examples for application of morphine from inspiring English sources
To determine the potential clinical utility of peripheral opioid action using a clinical model of cancer treatment-induced inflammation and pain that allowed for topical application of morphine in the damaged tissue (oral mucosa).
The application of morphine, meperidine and aminoglycoside antibiotics to intercostal muscle in vitro confirms effects previously demonstrated in rat muscle: (1) At equal therapeutic concentrations, meperidine has greater neuromuscular blocking effects than does morphine, but neither has significant effects at concentrations achieved in the serum clinically.
We investigated whether SH-SY5Y cells respond to the application of morphine and M6G.
Figure 3A shows inhibition of the amplitude of eIPSC following bath application of morphine (30 μmol L−1).
The rates of application of morphine, piritramide, or non-steroidal anti-inflammatory drugs were comparable (Tables 5 and 6).
Average concentration of glutamate release before and after application of morphine (10 μM) from VTA synaptosomes (n = 6 samples from eight rats, p = 0.46).
C-Fos expression is inhibited by applications of morphine and non-steroidal anti-inflammatory drugs (NSAIDs) [ 15- 18].
H-89 (10 μM) alone had no significant effect on GABAergic eIPSCs in slices of the FBC model (0.1 ± 2.7% inhibition, n = 15) before application of oxycodone or morphine.
This dose lies in the range of morphine applications usually used for locomotor assessment in arthritic animals [ 19].
In the case of morphine, microiontophoretic application to cat Purkinje cells induces either excitatory or inhibitory responses (i.e., an increase or decrease of the firing rates, respectively) [48], [49].
More importantly, when we clamped the membrane potential of VTA-DA neurons in the reversal potential of Cl− channels to remove sIPSCs, instead of using the intracellular or bath application of a GABAA antagonist, morphine still promoted presynaptic glutamate release in VTA-DA neurons.
