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Palmer, A. E., Qin, Y., Park, J. G. & McCombs, J. E. Design and application of genetically encoded biosensors.
Before industrial application of genetically engineered bacteria and yeasts, several steps have to be taken.
Taken together, our study provided the experimental basis for clinical application of genetically engineered lymphocytes; moreover, we also evaluate a new and interesting cell therapy protocol.
In addition, examples of the photochemical control of protein function through the application of genetically engineered natural-light receptors are presented.
In this review, we summarize several major fast calcium signaling pathways and discuss the recent developments and application of genetically encoded calcium indicators to detect these pathways.
Recent developments in establishing mouse models that closely resemble human lung cancers involve the application of genetically engineered mouse models (GEMMs) for use in drug efficacy studies or to guide patient therapy.
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Connecting the individual achievements into a coherent whole will enable the application of genetically-encoded biosensors in industry.
The rapid development of genetic engineering and extensive applications of genetically engineered (GE) animals have provided many research benefits, but concerns have been raised over the potential environmental impact of transgenic animals.
Molecular pharming is one of the applications of genetically modified crops and livestock for the production of pharmaceutical proteins.
Experimental applications of genetically encoded unnatural amino acids are highlighted with key reports illustrating their potential in addressing challenging biological questions.
Existing applications of genetically encoded fluorescent sensors allow imaging, in real time, of the production of H2O2 and studying its involvement in inflammatory responses, as well as activation of the oxidation-sensitive transcription factors HIF and NRF2.
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