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The process was optimized by application of factorial design and response surface methodology.
The biodiesel production process was optimized by the application of factorial design 24 and response surface methodology.
The application of factorial design gave a statistically systematic approach for the formulation and optimization of nanoparticleswith the desired particle size, %drug release and high entrapment efficiency.
The aim of this study was to optimize and assess the potential of nanostructured lipid carriers (NLC), prepared by the hot ultrasonication method, as carrier for methotrexate (MTX), highlighting the application of factorial design.
The objective of this study was the preparation, physico-chemical characterization and statistical optimization of cationic solid lipid nanoparticles (SLN) prepared by the PIT method as potential carrier for gene therapy, emphasizing the application of factorial design in such a kind of studies.
The effects of operating parameters such as applied current intensity, electrolysis time and initial benzoic acid concentration on the degradation and mineralization efficiency were investigated with the application of factorial design methodology and simple linear models describing and predicting adequately the removal of the substrate and DOC were developed.
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Application of factorial designs leads to methanol/water (80 20 (v/v)) as the best extraction solvent for the pulverised plant material and to a shaking bath for 30 min as extraction method.
Several examples are given of the application of this program including the use of factorial design experiments to determine the optimum conditions for formation of a chromate-free conversion coating on hot dipped galvanized steel.
The paper presents the application of the factorial Design of Experiments (DoE) to evaluate the influence of process parameters on the physical characteristics of ceramic microneedles (CMN).
This paper introduced a method to guarantee the correct estimation of speedups and the application of a factorial design on the analysis of PEA performance.
Application of a factorial design technique aided analysis of four process variables: temperature (30 70 °C), oil/alcohol molar ratio (1 6 1 10), catalyst amount (0.5 1.5% w/w), and reaction time (0.5 2.0 h).
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