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The main aim of targeted application of complement inhibitors is to reduce any potential side effects whilst trying to treat a condition [66].
In contrast to inhibitors of the coagulation cascade, the clinical application of complement inhibitors is still in its infancy as robust data demonstrating clinical benefits are still being produced.
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By identifying multiple discrete steps in the cytotoxic pathway for nucleated cells our findings may inform future development and more effective application of complement-fixing mAbs to cancer treatment.
Currently available experimental NMO models depend not only on the presence of human NMO-IgG, but also (in mice) on the application of human complement or (in rats) on the injection of large numbers of CNS antigen-specific T cells or adjuvant-assisted immunization with CNS antigens.
Thus, the application of FSA complemented with conventional gene deletion analysis will provide researchers with a wider choice of potential metabolic engineering targets for stain improvement, which will be beneficial to the field of systems metabolic engineering.
The virtual lab is made of a web-based application to complement experimental laboratory training, allowing students to prepare their experimental practices before going to the lab, and to review them at any time afterwards.
For some therapeutic applications however, activation of complement and FcγRs are best avoided.
The application of ultrasound can complement the prevailing lignocellulosic biomass pretreatment approaches such as alkali treatment, resulting in enhancement in the performance and efficiency.
Current environmental trends and developments restrain the use of synthetic chemicals and procure the application of alternatives that complement an integrated pest management approach that also includes genetic, biological and cultural control measures.
Application of GLIA can complement quality appraisal in identifying guideline deficiencies.
It can be calculated from the BEM matrix by repeated application of the Schur complement to eliminate all the unknowns in Eq. (3) except for the cortical and scalp photon densities.
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