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However prolonged application of circulation or aeration may have a different effect.
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Nowadays, the application of natural circulation due to safety margins that provide for cooling the nuclear reactor cores has drawn the attention of researchers and designers in this context.
In particular the application of extracorporal circulation, that is, cardiopulmonary bypass (CPB) with distinct contact between blood and artificial surfaces induces complement system, leucocyte activation and the release of cytokines, nitric oxide and oxygen-free radicals [ 19, 20].
The stability and steady-state characteristics of natural circulation are important for the applications of natural circulation loops (NCLs).
It should be stressed, that the application of o-cresol circulation in the synthesis dramatically improved selectivity of the process (compare Figure 12b and d).
Focus has been on the application of a microvascular circulation perfusion indicator to identify the endpoint during the resuscitation [ 26].
Although life salvaging, this procedure, by the application of a modified circulation and the forced passage of blood through a number of filters, activates endogenous inflammatory mechanisms and induces chronic release of molecules resulting in an increased production of reactive oxygen species [reviewed in [ 4, 5]].
The purpose of this research is to study, identify problems of the application of the entrance and circulation facilites as well as to produce alternative solutions to those problems with an approach to universal design in the shopping centres around Surabaya.
Here is what you get at the Hotel Inter-Continental in Hong Kong: a dry-skin brushing to stimulate circulation, the application of a spearmint-scented exfoliating body polish to remove the dead skin cells, an aromatherapy body massage, a luxury aromatherapy facial and, finally, a "stimulating" foot massage.
In healthy subjects, the sublingual microcirculatory physiological reserve can be assessed non-invasively by topical application of nitroglycerin without affecting systemic circulation.
The same has been demonstrated for regional perfusion after local intravascular application of NG into the arterial circulation of the arm [27] and leg [26], as well as microvascular flow velocity after transdermal application to the forehead [13].
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