The phrase "application has widened" is correct and usable in written English.
It can be used to describe a situation where the scope or range of an application has increased or expanded.
Example: "Over the years, the application has widened to include various new technologies and methodologies that enhance its functionality."
Alternatives: "scope has expanded" or "range has broadened".
The spectrum of amylase application has widened in many other fields, such as clinical, medicinal and analytical chemistry; as well as their widespread application in starch saccharification and in the textile, food, paper and pharmaceutical industries [ 17- 20].
Despite its use in starch processing industry and other related areas, currently the scope of α-amylase application has widened its range to other fields like, clinical, medical, and analytical chemistry as an arrival of new frontiers in biotechnology which ranked α-amylase as the first among the various extra cellular enzymes [ 8].
With the advent of new frontiers in biotechnology, the spectrum of amylase application has widened in many other fields, such as clinical, medicinal [ 22], and analytical chemistry as well as their widespread application in starch saccharification, food and brewing industries, baking, and preparation of digestive aids.
On the other hand, the sphere of application of artificial neural networks has widened covering such endeavours of life such as medicine, finance and unsurprisingly engineering (diagnostics of faults in machines).
On the same platform mineralization of other nanoparticulate delivery system which has widened their application drug delivery will be discussed.
Recently, as already mentioned, usage of UAS has widened its application to commercial and energy inspection operations, power transmission line inspection, gas and oil pipeline monitoring.
The development of smaller radiation sources has widened the application of brachytherapy to cancers of the nasopharynx, esophagus, bronchus, lung, and esophagus [ 6– 8].
While RAD-Seq and GBS have been very successful for certain applications, several limitations have become apparent as adoption has widened.
The application of the concept of pathogen-derived resistance (PDR) has widened the horizons of virus control.
Tufts has widened its scope.
