Although HDL subclass measurements have been widely used for scientific purposes, practical clinical application is not well established yet, and there is an ongoing debate on whether lipid subclass measurements should be implemented into clinical routine [4], [5], [8].
Type VI secretion systems are a relatively new discovery and their application is not well understood.
Remote monitoring technology promises earlier discovery of ICD system integrity (generator/lead) problems, but clinical application is not well tested.
However, the molecular basis underpinning the reduced UV exposure-induced skin damage by ADSCs application is not well understood.
Traditional mainframe core banking applications are not well suited to the digital economy.
Shankodi-Jangwa coal, Garin Maiganga coal and Tai coal are newly discovered Nigerian coal deposits; their ranks and suitable applications are not well known.
However, some emerging video applications are not well characterized by the down-link model but rather follow an up-link model, where some simple devices deliver information to a central, eventually rather complex, receiver.
Moreover, most of the time, many scientific software applications are not well documented, which also increases the level of complexities at the user end.
Potential atmospheric dispersal and residence time of organophosphates after agricultural applications are not well understood and are driven by many interwoven factors, including application methods, tillage practices, irrigation techniques, temperature, sunlight, rainfall, and wind (Bedos et al. 2002; Racke 1993; Whang et al. 1993).
Science is a collection of theories, practices, research traditions and world-views whose range of application is not well-determined and whose merits vary to a great extent.
