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We declare that the consent for publication is not applicable to this study.
Since several items required in quality reviews [46, 47] were not applicable to this study, the quality of the articles was judged as low, medium, or high as proposed by Petrén et al [48].
Since the APACHE III was originally designed for use in intensive care unit (ICU) patients, the score has been modified by excluding variables that are not applicable to this study population [21], [24], [25].
SOLAR is a computer package based on the variance-component method that performs linkage analyses for quantitative traits in pedigrees of arbitrary size and complexity, and was applicable to this study's large, complex pedigree with inbreeding loops and multiple matings.
Last, measurement errors in exposure are clearly applicable to this study.
Therefore, available evidence may not be completely applicable to this study.
Similar(37)
Not applicable to this retrospective study.
The only inclusion criteria applicable to this observational study were those related to the MADIT-II publication: MI one month or more before entry, LVEF lower than 30%, without coronary revascularization within the preceding 3 months.
This is particularly applicable to the study of bilateral breast cancer because both radiation dose and genetic susceptibility have important etiologic roles, possibly by interactive mechanisms.
The model presented in this report is applicable to the study of cell killing mechanisms in other cases such as hydrogen peroxide H2 O2 induced cell death in neurodegenerative diseases.
Should this technique be applicable to the study of other diseases, it could possibly provide a low-cost, low-labor requirement method for identifying potential target genes in diseases with poorly understood mechanisms.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com