The knowledge generated in mouse models, even in humanized mouse models, is not directly applicable to humans.
"Something more applicable to humans," she said.
The studies in rodents aren't necessarily applicable to humans.
First, phytoestrogens behave differently in different species, so animal studies are not applicable to humans.
As a member of Nurse's lab, Melanie Lee proved that his work in yeast was applicable to humans, a revelation that captured the attention of the medical community.
The important questions are: what is in the blood of the younger mice that impacts the ageing process, and is it applicable to humans?
But to prove a drug works, which would require exposure to the pathogen, animal tests can be used if there is reason to believe the results will be applicable to humans.
Whether the findings are applicable to humans remains to be seen but, if so, they could pave the way to treatments for diseases such as retinitis pigmentosa and glaucoma, which cause blindness by killing off cells in the retina.
In making its decision, the E.P.A. found that while one strain of female laboratory rats got ovarian and mammarian cancer after exposure to atrazine, the biological mechanism was not applicable to humans.
Drugs that mimic oxygen deprivation could restore the production of pyramidal neurons in premature babies, and redress the resulting imbalance of excitation and inhibition, but more research will first be needed to determine if the findings of the animal experiments are applicable to humans.
Nonhuman primates were used to define myoblast transplantation strategies applicable to humans.
