This method is therefore applicable to clonal pathogens that evolve almost entirely by point mutation, as well as to moderately recombining pathogens, in which recombinant parts of the genome can be identified computationally [ 53- 55] and considered as a single 'site'site
These results are relevant to PRRSV control or elimination projects at the herd, regional, or national levels, but the results are also broadly applicable to contagious pathogens of swine for which oral fluid tests of equivalent performance are available.
A point of care device utilising Lab-on-a-Chip technologies that is applicable for biological pathogens was designed, fabricated and tested showing sample in to answer out capabilities.
We demonstrated the validity of a novel approach for genomic-scale prioritization of drug targets applicable for any pathogens of medical and socio-economic importance.
Our assay will be useful to study the temporal sequence of signaling events the lead to the formation of cortical plaques during gonococcal infection and should be applicable to other pathogens that generate T4P including N. meningiditis, or Pseudomonas aeruginosa.
In some cases, immunological mechanisms relevant to biodefense are broadly applicable for many pathogens and may be most efficiently studied using model systems.
Furthermore, the model is currently focused on salmonellae and may not be applicable to other pathogens that do not meet certain prerequisites.
Although the methods are, in principle, applicable to intracellular pathogens, some aspects unique to the parasites may be crucial for obtaining relevant computational results.
This host-dependent mechanism of transient antibiotic resistance is applicable to multiple pathogens and has implications for the development of more effective antimicrobial therapies.
This may suggest that for evolution through growth-bottleneck cycles (which applies not only to laboratory situations, but is likely also applicable to many pathogens), the bottleneck size interacts strongly with the population size and other parameters to determine the dynamics of the evolutionary process [ 17, 18, 63].
