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Our approach of characterizing sequence diversity through targeted gene synthesis coupled to high-throughput screening technologies is a broadly applicable paradigm for a wide range of biological problems.
The capability to quantitatively compare data from individual samples against a large-scale annotated reference database represents a widely applicable paradigm for the analysis of all types of high-throughput data.
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The purpose of this forum is to cut this Gordian knot by documenting applicable paradigms, available resources, and scientific findings.
One major methodological issue is the difficulty of finding universally applicable paradigms that can be standardized and that are ecologically valid for the species to be compared.
One major reason for this is that it is very hard to find universally applicable paradigms that can be used to investigate the same cognitive ability or 'general intelligence' in several species.
Our approach, moreover, takes steps towards providing a unifying paradigm applicable to both submodular minimization and maximization, problems that historically have been treated quite distinctly.
Nevertheless, many of the concepts established from their study can be considered fundamental tenets of an evolving stem cell paradigm applicable to many regenerating cellular systems.
In conclusion, rare RBC mutations such as PK deficiency and GR deficiency resist malaria infection and may provide protection by the same paradigm applicable to widespread mutations such as those affecting hemoglobin, G6PD, or membrane proteins.
It further provides a paradigm applicable to other stem cell populations for establishing robust cell purification strategies and functional gene expression profiles.
The highly complex data generated by mass cytometry induced the development of new paradigms applicable also to flow cytometry.
This chapter focuses on the wide variety of specific behavioral paradigms applicable to assess learning and memory in rodents.
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CEO of Professional Science Editing for Scientists @ prosciediting.com