AAV, adeno-associated virus; FDA, US Food and Drug Administration; HSV-tk, herpes simplex virus thymidine kinase; IL-1Ra, interleukin-1 receptor antagonist; N/A, not applicable; OBA, Office of Biotechnology Activities PII, principal investigator; TGF-β1, transforming growth factor-beta-1; TNFR, tumor necrosis factor receptor.
Data integrity was confirmed by data checks within the database, resulting in queries to the investigator where applicable.
Guarantor: Professor Janet A Dunn Not applicable A NIHR senior investigator award for Professor Janet Dunn funded this research.
Interviews and FGDs were conducted in the local languages, French or English (where applicable) by the principal investigator (PCC) or trained local research assistants.
We also found that the sheer size and complexity of the initiative requires attention to a host of management challenges that would not be applicable to traditional individual investigator awards.
Interview where applicable would be held with investigators and or study staff about their training, knowledge of the research regulations, study related meetings, any other studies at the site and how they handled study participants.
In general, the end users found the features supported by CrimeFighter Investigator to be applicable to their work, and in some cases our integration of features was found to be more useful than existing tools (such as Analyst's Notebook, see summary of evaluated tools earlier in this section).
Specifically, in the training session, the investigator explained each applicable intervention and how to use it.
The study protocol was approved by the local independent ethics committee or institutional review board, as applicable, at each of the investigator sites.
As well as following this statement of basic values of ethical biomedical research, investigators should follow all applicable rules and regulations, including national laws and regulatory guidelines.
