We note that the test procedures proposed here can also be applicable if we are interested in testing non-inferiority with respect to the ratio of sensitivities and the ratio of specificities.
The test database is among the largest used in similar studies and suggests that the algorithm is robust and applicable in various testing conditions.
We also demonstrate that our construct works in medaka, another model fish test species, suggesting the transient assay is applicable for testing oestrogenic chemicals in fish generally.
On the other hand, feature-adaptation methods such as the cross transform does not require the knowledge of the test environment and availability of parallel training data, making them universally applicable in all test environments.
In this paper it is shown that pyrosequencing is applicable in toxicity tests to investigate the modification in DNA methylation upon exposure to chemicals in vitro.
To make the protocols broadly applicable, testing among various physical therapists practicing in different settings is needed.
However, multiple crossovers with randomly assigned treatment periods, with a complete random order or a random starting day may generate specific methodological problems and need new statistical models before being applicable in clinical drug testing.
The high prevalence of low-level methylation demonstrated in this study underlines the notion that evaluation of the low-level methylation in healthy tissue is critical for biomarker development and that only methods that allow for a definition of a cutoff for background methylation levels are most likely to be applicable in clinical methylation biomarker testing.
If applicable in the in vitro test, the Student t test was used for the comparison in paired groups.
In only one eye (1.8 %) in group V, the presence of vitreo-papillary adhesion was noticed during vitrectomy.> -wrap-foot> *Mann–Whitney U test **Chi square test ***: Fisher's exact test †Not applicable In group B, encircle, circumferential segmental buckle, and radial buckle were performed in 9 eyes (12.5 %), 62 eyes (86.1 %) and 1 eye (1.4 %), respectively.
