Sentence examples for applicable dosing from inspiring English sources

The point we wish to emphasize is that typical regulatory safety assessment studies conducted in accordance with GLP a) must follow agency test guidelines to assure use of relevant test systems, sufficient and applicable dosing protocols, and adequate dose groups and sizes, and b) must evaluate specific end points that regulatory organizations consider validated.

When applicable, dose-reponse of multiplicity of infection (moi) were performed to confirm/validate our findings.

However, a safe, clinically applicable dose proved to be moderately effective in this porcine calvarial defect model.

Dosing records included the amounts, dosing times, rates of infusion and infusion duration (when applicable, doses associated with tube flush were considered bolus).

However, several studies have reported that serum L‐ASNase concentration is sustained above 1 U/mL even 24 h after the administration of clinically applicable doses of L‐ASNase.

These results are especially exciting given that isoflurane is already FDA approved for use in the SAH patient population and that administration of isoflurane at a clinically applicable dose and at a clinical relevant time point provided robust protection against several contributors to SAH-induced DCI.

The primary objective of this study was to determine the effects of in vivo scanning at 2-week intervals on bone healing of a critical sized radial defect in rabbits and to investigate the effect of this radiation protocol on bone marrow cell viability using clinically applicable radiation doses.

If applicable, the dose escalation could be performed according to the predefined schedule.

This study has shown that the described simulation method is applicable for dose levels down to 10 mAs (tube current 20 mA with rotation time 0.5 s).

A Planning Organ at Risk Volume (PRV) expansion of 2-5 mm will be added for OAR such as the spinal cord, oesophagus, intestine,… (if applicable), and dose constraints apply to this PRV.

So, it is important when determining the drug dose for the model animal to use a dose applicable to a 10 kg dog [ 8].