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The accuracy of computationally inferred haplotypes increases with sample size, and although ever larger genotypic data sets are being generated, the fact that existing methods require substantial computational resources limits their applicability to data sets containing tens or hundreds of thousands of samples.
The conciseness and powerfulness, together with the applicability to data with relatively low SNP density, are convenient for analyses of genotype data produced by DNA microarray or other technologies.
We also demonstrate MSNet's applicability to data generated from different MS pipelines.
This unbiased association is strongly supported by prior studies finding MMP [ 35, 36] and VEGF [ 37] activity strongly associated with the recurrent phenotype [ 37] and supports Literature Lab's applicability to data from human samples.
To compute the pairwise alignment, we use dynamic time warping (DTW) due to its applicability to data with non-linear time scale distortions (Itakura, 1975; Kruskal and Liberman, 1999; Sakoe and Chiba, 1978).
In doing so, it has the advantage of generating models that can be described by continuous smooth dynamics, which then allow for accurate estimates of parameters for use in the analysis phase, effective data noise reduction through curve smoothing, and applicability to data with irregular time sampling schedules.
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DISTMIX inherits the main advantages of DIST, i.e. speed, not requiring genetic data access and applicability to pedigree data, while gaining the capability to accurately impute association summary statistics from multi-ethnic studies.
Thus, this approach has potential for applicability to field data.
An extensive evaluation of Merkurion in real-world datasets has proven its effectiveness and broad applicability to many data domains.
Furthermore, The LM NS method (introduced in the first part) is used to parametrically model the AMS, investigating its applicability to real data, to account for temporal trends in the moments of the time series.
Two classical filtration models were evaluated to assess their applicability to test data obtained from filtration of a high level waste (HLW) sludge sample from the Hanford tank farms.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com