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She described the requirements (e.g., applicability, sensitivity and robustness as well as data interpretability) such bioassays must meet to be of use to regulatory authorities and concluded that national and international standardization of bioassays increases the chances of incorporating these tools into regulatory frameworks.
Recently, with the development of multi-color flow cytometry and new markers, MFC method for MRD evaluation based on LAIPs is increasingly used in the management of ALL with high applicability, sensitivity and specificity and has been regarded as an important counterpart of PCR detection.
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Recent reports on the applicability and sensitivity of real-time RT-PCR (30– 32) for noroviruses also offer new possibilities to enhance its sensitivity.
The applicability and sensitivity of MGE-PCR in epidemiological studies was demonstrated by direct amplification of T. gondii from sheep tissue samples.
It identifies the advantages and disadvantages of using different data sources as well as the applicability and sensitivity of existing indicators in detecting visible landscape change.
Recently we showed the applicability and sensitivity of the RNA-based sandwich hybridisation assay (SHA) for detection of Gram-negative cells in environmental samples [Leskelä, T., Tilsala-Timisjärvi, A., Kusnetsov, J., Neubauer, P., Breitenstein, A., 2005.
The inhibition by other FDA-approved PR inhibitors proved that the applicability and sensitivity of the assay is not limited to IDV, validating once again the ability to utilize eGFP expression as a biosensor for PR activity in SupT1 cells.
Its strength lies in its broad applicability and sensitivity.
Doubts remain as to the applicability and sensitivity in the specific context of IBD patients in the transitional age.
We have demonstrated the applicability and sensitivity of IS-RT-PCR for the examination of MMP gene expression both in vitro and in vivo.
To assess the applicability and sensitivity of the PLS models, optimized PLS prediction models from low ranges of parasitemia series (0 5%, 0 0.1%, and 5 10%) were used to predict parasitemia concentration of a series of infected RBCs with rings as unknown or blind samples.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com