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The applicability, safety, and effectiveness are the main advantages of this protocol when compared to similar staining procedures used in the family.
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In order to address the possible complications following such treatment, we designed a study to evaluate the applicability and safety of repeated IM injections of MSC-NTF cells in mice.
We also demonstrated the applicability and safety of this approach in metachromatic leukodystrophy (MLD) mice.
The applicability and safety of this strategy have been well documented, and PEGylated proteins have been used in clinics for years.
We believe that the applicability and safety of the LMA in ICU patients, some of whom require high degrees of ventilatory support, are questionable.
Additionally, data are being collected in the intervention group relating to the applicability and safety of the Hobart method (Table 2).
The previous sequence is a typical example of the steps necessary to test newly developed interventions for efficacy, applicability and safety.
The under-representation of older adults from initial trials showing the benefits of tight glycemic control led to uncertainty regarding the applicability and safety of the intervention in older persons (9).
This common approach has however a limited applicability for safety-critical tasks and for partially blindfolded activities heavily relying on haptics, both commonly found in surgery.
This taught us a valuable lesson; innovations in surgical techniques should not be rapidly implemented until all aspects including applicability, feasibility and safety have been fully tested.
Drug delivery with microbubbles and ultrasound is gaining more and more attention in the drug delivery field due to its noninvasiveness, local applicability, and proven safety in ultrasonic imaging techniques.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com