Despite the maturity and convenience of JKR theory to describe adhesion, the applicability of JKR in the case of compliant layers on elastic substrates is a topic of current research.
Both experimental and numerical investigations were undertaken to determine the effectiveness and applicability of the method in the case of bridge superstructures.
The predicted effective elastic properties are in good agreement with the available experimental data, demonstrating the applicability of the FEM in the case of tension in the primary loading direction z.
Previous studies [59,64-66] highlightedghthe the usefulness of considering the ensemble standard deviation as a domain applicability (DA) measure, specially in the case of RF models, where the calculation of the standard deviation along the trees is straightforward [59,64].
However, doubts about the general applicability of this model in the case of S. pneumoniae have recently been risen [34], suggesting that the role of host immunity in determining the population variability of antigens could be less important than previously assumed.
This may lead to the conclusion about restricted applicability of this mechanism in the case of hb expression.
Since the late 1970s, treatment of chordoma has traditionally relied on en bloc surgical removal [ 25]; this technique has been very effective for sacral chordomas, although its applicability is obviously limited in the case of clival chordomas.
This lack of practical applicability was painfully obvious in the case of an 80-year-old woman (no. 8 and 24) with an incompletely removed lesion described as benign adenomyoepithelial tumour.
