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Although data from clinical studies of the impact of ECMO on altering the PK of drugs used in patients on ECMO will have great applicability for optimisation of pharmacotherapy, mechanistic research is required to identify the specific factors contributing to these PK changes.
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The applicability of the genetic algorithm was tested for optimisation of large solar hot water systems.
A Genetic algorithm is used for optimisation.
This suggests the need for optimisation of the PFGE programme.
If required, the research fellow gives feedback for optimisation.
This variability clearly shows both the need for optimisation and for careful control of process conditions.
§ 175.112 Specific applicability for individual parts.
These measures also have applicability for researchers.
Thus our modular synthetic approach will facilitate the optimisation and application of targeted Zn2+ sensors for biology, allowing the manufacture of tailor-made probes, such 6, with applicability for the study of Zn2+-signalling and insulin exocytosis.
Applicability: for any patient in any setting.
Concerns for applicability for all four domains were predominantly low.
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