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A series of new anti-cancer pyrimidine acyclonucleoside-like compounds were designed and synthesized by structural modifications of 5-fluorouracil, a drug which causes considerable cell toxicity and morbidity, and we evaluated their applicability for differentiation therapy in human rhabdomyosarcoma cells.
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To demonstrate the methods applicability for estimating differentiation efficiencies, we carried out a simulation study.
In addition, in comparison with the GPS, the COP-NLR may have higher applicability for estimation of SIR, because proliferation and differentiation of cellular components occurs much faster than protein synthesis when inflammatory cytokines are released.
Language provides more opportunities for differentiation.
The grid is a useful device for differentiation.
"We are desperate for differentiation from the Tories," one Lib Dem strategist told me.
The chain rule for differentiation reads.
There are also opportunities for differentiation in pricing.
Qatar's strategy for differentiation is their 'compact bid'.
Grills are also becoming an opportunity for differentiation and self-expression, particularly for men.
Both the brevity of the answers, and the enthusiasm for differentiation come, however, at a cost.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com