Sentence examples for applicability concerns from inspiring English sources

Fig. 2 Risk of bias and applicability concerns.

Table 2 Risk of bias as assessed with the Quadas-2 tool Study Risk of bias Applicability concerns Patient selection Index test Reference standard Flow and timing Patient selection Index test Reference standard Chouker, [20] + ?

Applicability concerns were low.

There were low applicability concerns.

All studies had a low risk for applicability concerns (patient selection, index test and reference standard).

All studies were in intensive care, with either a high risk of selection bias or high applicability concerns.

A low applicability concern indicates better quality compared to high or unclear applicability concern.

While these technologies have made genome engineering widely accessible, the ability of programmable nucleases to cleave off-target sequences can limit their applicability and raise concerns about therapeutic safety.

We conclude that cyclic compression enhances matrix stiffness, but stimulation time should be kept short and growth factors should be left out in this system with regard to clinical applicability and financial concerns.

Applicability: Are there concerns that the included patients and setting do not match the review question?

Applicability: Are there concerns that the target condition as defined by the reference standard does not match the question?