Furthermore, current in vivo testing routines were not specifically designed to assess the endocrine disrupting properties of chemicals, whilst in silico and in vitro methods have only limited applicability and availability for this purpose.
The zwitterionic polymers are promising nonfouling biomaterials due to the simplicity of synthesis, ease of applicability, abundance of raw materials, and availability of functional groups.
However, the applicability of such solutions greatly varies with the nature and availability of the tissue of interest: microdissecting individual cells spread throughout a tissue section can for instance be very time-consuming.
Notably, the applicability of polyphenol biomarkers in epidemiologic studies relies on their ability to reflect the dose ingested, reliability over time, and availability of appropriate analytic methods for their estimation in biospecimens.
A clear advantage of this method is its easy applicability, the immediate availability of results and its suitability for infarct volume evaluation [15], [33] [36].
Typically, this involves identifying by direct interrogation the lead's product applicability, availability of funding, and time frame for purchase.
Accessibility, applicability, credibility, the availability of other interventions, and equity/fairness were also worth considering (medians between 3 and 4) but in the context of decision making were viewed as being not as important as the other types of evidence above.
Prognostic evaluation of the patients without CT scan findings may have limited applicability considering the availability of CT scans in the majority of the trauma centers.
The use of EBDM in public health agencies depends on many factors, including the training and experience of the workforce, organizational resources and climate (e.g., funding, buy-in from leadership and elected officials), and the availability, applicability, and dissemination of evidence on a given topic [ 16- 21].
