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As Sunitinib and Sorafenib share common targets [ 5, 6], the differential effect of these drugs on PTEC appears unexpected and of interest.
Considering the Noxa induction in erythroid progenitors and its regulatory role upon cytokine deprivation, the absence of an effect of Noxa-ablation on erythropoiesis appears unexpected.
Although our gnd tree topology appears unexpected compared with the prevailing view of plastid evolution [ 38], several gene phylogenies that suggested imprints of gene transfer between Euglenida and Stramenopiles have been reported.
The unexpected nature of a gout diagnosis for women, particularly if this diagnosis also appears unexpected to the doctor, can lead to a lack of confidence in this diagnosis.
IL-2 has previously been shown to antagonize conventional Th17 differentiation in murine cells [ 33], so the synergistic effect of IL-2 with IL-1β to promote IL-17 induction in human Treg cells appears unexpected.
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As a result, new opportunities appear, unexpected until now.
Other gene expression profiles could appear unexpected.
The expression on melanoma cell lines of such molecules which are normally expressed on immune cells might appear unexpected.
This result may appear unexpected at first, given that therapeutic insulin can be dosed to produce virtually any desired blood glucose value [ 1, 2].
As a result, it does not appear unexpected that there is no mtDNA variation, much less reciprocal monophyly, while there is substantial variation and differentiation for microsatellite and MHC loci.
At a first glance, our results showing an association between low expression of proliferation-related genes and benefit from weekly paclitaxel could appear unexpected since it is generally assumed that chemotherapy is not efficacious in tumors with low proliferative activity, such as Luminal A tumors.
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CEO of Professional Science Editing for Scientists @ prosciediting.com