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Importantly, the peptide-injection model appears to replicate the changes in cellular properties and brain microenvironments evident in inflamed brain in the progression of AD pathology.
Family-based linkage analyses have also been conducted in two studies, finding significant evidence for linkage at 12q12.22 (Vasa-Nicotera et al. 2005; Mangino et al. 2008) and 14q23.2 (Andrew et al. 2006), although neither study appears to replicate the other's findings.
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Some hogbacks appear to replicate the roofs of Viking longhouses with geometric tile patterns; others have strange dragon-like creatures hugging the ends.
Thus, treatment of BC cells with exogenous UA in vitro appeared to replicate the state of cells from more aggressive tumors with increased metastasis that have been associated with aggressive breast and colorectal cancer in patients with MetS[23, 138, 139].
iRBC can also induce MP from platelets and in an in vitro CM model these appear to replicate the effects of platelets on endothelial cells, and particularly to enhance iRBC cytoadhesion (Faille et al, 2009a, b).
In this report we have provided further support for the notion that there are QTLs for ACE unlinked to the ACE gene; our findings for chromosome 4, which appear to replicate the findings of a previous independent study, should be considered strong grounds for a more detailed examination of this region in the search for genes/variants which influence ACE levels.
Our modelling of trioecy, with just the outcross-fitness parameter, appears to replicate accurately the experimental transitions to selfing.
Further, whilst mtDNA replication intermediates in cells continuously cultured in normal medium are a mixture of those produced by strand-coupled DNA synthesis and RITOLS replication, the latter of which requires much less DNA ligation, mtDNA appears to replicate mainly via the strand-coupled DNA synthesis mode after the removal of ddC [3,5] (Supplementary Fig. 1).
Although we have not presented the results for off-movements of cattle from premises, the data are very similar and the traces appear to replicate those seen for the on-movements.
Experimental PG-induced uveitis appears to replicate to some extent the spectrum of human uveitis that occurs in patients with spondyloarthritis.
However, the paternal set appears to replicate properly and does not become abnormally phosphorylated before entry into the first mitosis (Swim et al. 2012).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com