Thus, urothelial neoplasms appear to develop and progress via at least two distinct pathways with different biological behaviour and clinical outcome; the papillary noninvasive and CIS/invasive pathways.
This question grows in part out of the realization that early on, cells and organs in most storage disorders appear to develop and function normally, and only later is this followed by insidious disease onset and progression.
In this regime, combustion occurs with spontaneous ignition, and it appears to develop without a visible and audible flame[4].
The fundamentals for a successful vaccine are strong (effective vaccines against other similar viruses have been developed, protective immunity appears to develop naturally after infections, and protection from Zika infection after vaccination with experimental inactivated virus and viral DNA-derived vaccines has already been achieved in mice and non-human primate models of disease).
The shear anisotropy we report is consistent with prior anatomical observations of this tissue and appears to develop through separate contributions from the matrix, the collagen fibers, and collagen fiber interactions.
"Our research shows that a potentially very harmful bias in adults emerges during middle childhood, and appears to develop across childhood," the study's lead researcher Rebecca Dore, a PhD candidate in developmental psychology at the university, said in a written statement.
The ventral system is particularly important for receptive language and appears to develop in early childhood, while the dorsal system shows a more protracted developmental course.
HCC has been regarded as one of the major complications of BCS, and appears to develop chronically with the progression of BCS [ 10, 19].
The first type arises primarily in younger patients and is associated with human papillomavirus (HPV) infection; the other form is seen mostly in elderly patients and appears to develop independently of HPV infection.
Once the immune system has been nudged into action by the T-VEC treatment, it appears to develop an enhanced ability to detect and attack cancer throughout the body.
