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C. elegans SYG-1's specification of proper synapse formation in vivo closely correlates with the heterophilic complex affinity, which appears to be tuned for optimal function.
The particular combination of fast and slow dynamics found in the Aplysia CPG appears to be tuned specifically to the range of environments in region "b" in Figure 5C, left.
In the cichlid genus Pundamilia, LWS opsin sequence and expression appears to be tuned to specific male color morphs [ 10].
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Each cell appeared to be tuned to up to eight different facial dimensions.
Few tech-stock investors appear to be tuned into this thinking.
Furthermore, MT cells appear to be tuned to disparity-defined slants [61].
Thus, in a 5' to 3' progressively folding scenario, these structures appear to be tuned to fold correctly and can easily catch the pseudoknot at the minimum free energy.
For LDH, for example, various isozymes all have the same active site architectures whether the isozymes are from psychrophiles, mesophiles, or hyperthermophiles, but their individual kcat and Km values appear to be tuned to operate properly at the respective temperatures.
Interestingly, the lack of structure in the input to the KCs, the small number of inputs, and the sparseness of their activity all appear to be tuned to maximize this dimension (Perez-Orive et al., 2002; Huerta et al., 2004; Caron et al., 2013; Gruntman and Turner, 2013) (Ann Kennedy, Columbia University Thesis).
V1rj3 appears to be narrowly tuned to sulfated estrogens and is more sensitive to E1103.
Thus, proteostasis capacity appears to be finely tuned to maintain a natively expressed proteome.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com