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In wild-type, FAF effects on WUS are likely to be exerted only by FAF2 and FAF4, which are the two FAF genes expressed in the centre of the shoot and/or inflorescence meristem in a domain that appears to be overlapping with the site of WUS expression.
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Applying siRNA-mediated knockdown to endogenously expressed PKC isoforms identified PKCα as a key regulator of ADAM17-dependent shedding, whereas PKCδ and ERK contribute to both constitutive and stimulated shedding, in what appear to be overlapping mechanisms.
The authors find that different targets respond differently to these sequence substitutions, and propose that there are different binding determinants within what appear to be overlapping sites.
Other tRNA genes which appear to be overlapping by 1 to 2 bp at the 3' end with another gene or tRNA may in fact be lacking these bases.
In addition, the melting profiles of samples heterozygous for the common c.1187G > A and for the rare c.1276C > T (p.Arg426Cys) mutation appeared to be overlapping.
According to the asymmetry of the desorption peak, multiple desorption peaks appear to be overlapped.
There appears to be overlap in the genetics of schizophrenia and bipolar disorder.
Srebp-2 is associated with cholesterol biosynthesis, while the Srebp1 proteins are associated with fatty acid synthesis [ 27], although there appears to be overlap in the genes that are responsive to these transcription factors [ 34].
However, in many cases, there appeared to be overlap in the work that implementing partners are doing.
The synonymous codon usage appears to be significantly overlapping for C. auris 6684 and C. lusitaniae which correlates and supports the relatedness found in the results of phylogenetic analyses (Figs. 3a and 4c).
The biomarker results indicate that PFS and OS benefit in patients with high EGFR gene copy number in their tumours appears to be derived from overlapping EGFR mutation positivity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com