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Even if CNS1 appears dispensable for Treg development in the thymus, TGF-β may play a role in the thymic differentiation of Treg.
However, PIP3 production appears dispensable for cell polarization.
In addition, the FA pathway appears dispensable for class switch recombination.
Indeed, eEF1γ appears dispensable for translation, its absence doesn't seem to affect global rate of translational elongation.
Only if there is more than one RNase ZL gene, the general dual nuclear/mitochondrial localization of RNase ZL appears dispensable.
Similarly, this result also explains why ectopic expression of OCT4 and SOX2 appear necessary for the reprogramming process but NANOG appears dispensable [10], [24], [25], [38].
Similar(32)
Yet there have been times this summer when those qualities actually appeared dispensable.
In contrast, siRNAs appear dispensable for major developmental events under uniform laboratory conditions.
Thus both Bax and CKII appear dispensable for the basal JNK1/JNK2 apoptotic pathway.
Both TRAF6 autoubiquitination and the TRAF6 RING finger domain appear dispensable for recruitment of the TAB1-TAB2-TAK1 TAB1-TAB2-TAK1 TAB1-TAB2-TAK1
Aurora kinase activity would therefore appear dispensable for DNA damage checkpoint abrogation and subsequent potentiation of cytotoxic chemotherapy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com