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The phrase "appeared to regulate" is correct and usable in written English.
It can be used when discussing observations or findings that suggest a certain level of control or influence over a process or system.
Example: "The study indicated that the new policy appeared to regulate the behavior of employees more effectively than previous measures."
Alternatives: "seemed to control" or "appeared to manage".
Exact(28)
Based on its intrinsic properties, FS appeared to regulate at least five different groups of molecules essential in the regulation of (i) gene expression (transcription factors), (ii) signal transduction (signaling pathways), (iii) inflammatory responses (cytokines), (iv) cell proliferation (cell cycle regulation), and (v) cell remodeling (via cytoskeleton apparatus).
Some OA derivatives were bactericidal to three of the strains and appeared to regulate gene expression associated with metabolism, haemolysis, and β-lactamase in vitro.
Some benzaldehyde Schiff bases were bactericidal to all the three strains and appeared to regulate gene expression associated with metabolism, hemolysis, and virulence, in vitro.
The gene variant appeared to regulate hundreds of other genes active in fat cells, changing the structure and function of those cells.
He and others discovered that in yeast, certain segments of DNA could "jump" from one location to another, and that these segments appeared to regulate the expression of whatever genes were nearby.
The antibacterial mechanism of the active benzaldehyde Schiff bases appeared to regulate the expression of metabolism-associated genes in E. coli, hemolysis-associated genes in B. subtilis, and key virulence genes in S. aureus.
Similar(32)
Ankyrin binding, therefore, appears to regulate the dynamic behavior of neurofascin and is the target for regulation by tyrosine phosphorylation in response to external signals.
VPS13D appears to regulate IL-6 production.
SVEP1 appears to regulate molecules of the leukocyte adhesion pathway.
Phosphorylation appears to regulate myosin thick-filament formation.
One gene appears to regulate the brain's ability to form new memories.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com