The phrase "appear to be significant" is correct and usable in written English.
It can be used when discussing something that seems important or noteworthy based on observation or analysis.
Example: "The results of the study appear to be significant, indicating a strong correlation between the variables."
Alternatives: "seem to be important" or "seem to hold significance."
However, nerve damage and radiotherapy appear to be significant risk factors for chronic pain.
But those studies did not consider the effects of casual use.Those effects appear to be significant.
Mr. Ravnsborg devoted most of his brief to discussing those procedural problems, which appear to be significant.
There did appear to be significant differences in self-reports of palpitations and motivation favoring the lion's mane group.
The reservations of top Republican senators about Russian conduct in general and Tillerson in particular appear to be significant – but Trump has called the party to heel before.
"The millions of victims of the first world war in Poland, Belarus, Ukraine and Russia don't appear to be significant enough for the German government.
Sometimes they appear to be significant, but I don't conclude from that that The Times's coverage was incomplete, just that editorial judgment was exercised.
Oddly, of the many historical examples cited in his book, Mr. Muensterberger skips over one that would appear to be significant.
Effects of the finite extensibility of network chains appear to be significant in double networks while the possible role of orientational crystallization cannot be excluded.
Furthermore, RGD and PHSRN appear to be significant in mediating this receptor ligand association resulting in the necessary signaling characteristic for macrophage adhesion and the subsequent development.
Like many people for whom diet and weight do not appear to be significant factors, I have long suspected my hypertension has both a genetic and an emotional component.
