The phrase "appear to be focal" is correct and usable in written English.
It can be used when describing something that seems to be central or significant in a particular context or situation.
Example: "In the discussion about climate change, the economic impacts appear to be focal to the debate."
Alternatives: "seem to be central" or "seem to be key".
We conclude, then, that while most HFOs appear to be highly focal, perhaps limited to a single cortical microdomain, there is a subclass of HFOs that have a large scale component, most commonly seen in association with interictal epileptiform events.
The effects on brain function associated with prenatal methylmercury exposure therefore appear to be multi-focal and permanent.
They have learned that in addition to the inherited mutation, somatic mutations in these same genes appear to be required to initiate the focal lesion development.
The two mechanisms, together with intraluminal seeding, appear to be strongly responsible for multi-focal disease as well as for localized and distant recurrences within the urinary bladder.
The FAK−/− phenotype is similar to that observed in the current study on Fmn1-IV, however, in contrast Fmn1-IV does not appear to be significantly localizing to sites of focal adhesion.
Two pathways namely the "p53 signaling cascade" and "focal adhesion" appear to be influenced to a comparable extent by targets both of dysregulated and of preserved miRNAs.
Many focal lesions may appear to be cystic on cross-sectional imaging.
Moreover, in diseased mice, we observed within the same perivascular lesion VSOP as discrete focal accumulations that appear to be co-localized with iba-1-positive cells, as well as diffuse VSOP accumulations which did not appear to be cell-associated.
More importantly, pathway analysis has revealed that the cell cycle or any of the proliferation-related pathways are not significantly altered at early stages, but instead, other pathways including the Renin-Angiotensin System (RAS), Wnt signaling and focal adhesion pathways appear to be affected at early stages of cystogenesis.
However the changes in focal adhesion in the human cells would initially appear to be contradictory to their migratory phenotype.
