Sentence examples for appear defective from inspiring English sources

Notably, all mutants appear defective in polymerization as compared to wild type FtsZ.

On the other hand, insulin resistance is accompanied by various degrees of impairment of the PI3K signaling [37], whereas the MAPK pathway does not appear defective in the state of insulin resistance [38].

However, such Gr1+CD11b+ cells appear defective and may actually suppress iNKT cells in tumor-bearing animals [45] We did not find evidence that supports a correlation between the presence of iNKT cells in TRAMP mice and either the efficiency of the Tag-specific CTL response or a decreased induction of tolerance toward Tag.

Mutant RNAPs appear defective in simulations compared to RNAP wild type.

However, these phage-derived genes now appear defective, as the sequence homology only partially cover the ORFs.

Subcellular localization studies show that in FCS-cultured cells, wild type UBIAD1 localizes to the Golgi, whereas the N102S and G177R mutants of the enzyme appear defective in Golgi trafficking and remain sequestered within the ER.

Furthermore, the cox-2 null animals were largely infertile, likely as a result of abnormal appearing, defective oocytes.

MicroRNA 21 processing appeared defective suggesting that post-transcriptional protein synthesis regulation is altered by disruption of tissue microRNA expression.

Because the rbbA and yhjD mutants appeared defective in the synthesis of proteins (Figure 4A), we assessed the translational fidelity of the mutants in vivo by examining the expression of full-length β-galactosidase (β-gal) from a template harboring out-of-phase nonsense codons in its coding sequence.

This system appears defective in type 1 diabetes, in which hypoglycaemia commonly occurs.

Interestingly, whereas both variants display intermediate activity with respect to transcriptional transactivation, only R1699Q appears defective in nuclear foci formation and only A1708V induced centrosome amplification.