Although array-CGH can be used to reveal deletions and amplifications, including imbalances associated with apparently balanced translocation, they are unable to detect balanced rearrangement events such as inversions and balanced reciprocal translocations.
Translocations in 13q are apparently balanced by CGC, and several studies have proven that balanced rearrangements do not imply a worse prognosis in CLL [ 4, 82, 86].
Near the chapel stands Barnett Newman's sculpture Broken Obelisk, a colossal impossibility, one point apparently balanced on another, supporting immense weight, forever suspended, forever incomplete.
But that temporal unease is apparently balanced out by the company's server and tools unit.
Cytogenetic analysis identified an apparently balanced reciprocal translocation, 46,XY,t(1;2)(q32;p25) which had occurred de novo.
Three individuals with apparently balanced translocations with a breakpoint within SATB2 or in a highly conserved region 3' of the gene have also been reported [5], [8].
Karyotypic analysis of the lymphocytes of a neuroblastoma patient revealed a de novo, constitutional, apparently balanced translocation between chromosomes 1p36.2 and 17q11.2 [7].
One such case with multiple laterality defects and sirelomelia was found to have a de novo apparently balanced reciprocal translocation 46,XY,t(2;6)(p22.3;q12).
Ciccone [49] et al reported that three out of four of such patients with apparently balanced translocations were actually unbalanced, and had complex rearrangements.
