I will show that the central early controversy over the roles of random genetic drift and natural selection in evolution has continued to this day, not withstanding the apparent technological refinements afforded by the availability of biochemical and DNA sequence data.
Since positional and displacement parameters are correlated, limiting model flexibility (constrained hydrogen positions) seems to make the onset of additional rotational motion more apparent in invariom refinement, whereas free refinement of positions and seems to lead to an over-parameterized model in HAR.
The raw excitement is easy to bring out, but Mr. Muti's readings also have refinement, as is apparent here from his shaping of the gently unassuming music that opens the Prologue and of the rippling depiction of the sea at the start of Act 1.
Literary historian George Călinescu notes that this fictional portrait shows: "The dignity in gossip, the boyar carriage, the refinement that the apparent vulgarity cannot bring to ruin, the blasé and cynical lechery".
During refinement it became apparent that the aldehyde carbon had oxidized to the carboxylic acid, to give compound 2 (Scheme 2), a finding confirmed by chromatographic analysis of the mother liquor.
The new Benj Pasek and Justin Paul (remember those names) musical is even better in December, thanks in part to the extraordinary acting company's continued refinements and their apparent love and respect for the characters they inhabit.
Two preoccupations were particularly apparent in Douglas's later work: refinement of her theoretical statements, notably in How Institutions Think (1986) and Missing Persons (1998), and a return to the analysis of the Old Testament that had been an important feature of Purity and Danger.
In all three complexes, defined | Fo|−| Fc|, ϕcalc electron density for the compounds was apparent from the early stages of refinement.
After molecular replacement and a few rounds of refinement, however, it became apparent that electron density in the vicinity of Cys 113 could not be fit by a single side chain conformation.
The Sony's detail refinement is even more impressively apparent versus the LG OLED in the Mad Max shot where Immortan Joe first looks down on an assembled crowd of his 'citizens'citizens
