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Nevertheless, the PIN lesions in these mice do evolve into cribriform lesions as an apparent progression event (Figures 6 and 7).
Such delayed responses following a period of apparent progression, have been observed following other immunotherapeutic strategies, such as anti-CTLA-4 therapy and may represent an early inflammatory response, followed by delayed disease remission[19].
We found one report describing apparent progression from biopsy-proven APSGN to dense deposit disease.
The exogenous hormones did not affect development of preneoplastic lesions but rather prevented their apparent progression to tumors.
These assessments were repeated at 1 month after the last course of treatment and on apparent progression.
An unchanged CCl would demonstrate that the apparent progression represented a prior, rather than a continuing decrease in GFR.
Similar(42)
The appearance of multiple apparent progression-forming modes suggests that vibrational displacements are large (i.e., large Huang Rhys factors, S = ∑ i n 1/2Δ i 2, where Δ i is the displacement for mode i.
The difference between observed and expected EDSS progression was less marked when we restricted the analysis to the subgroup of patients with the year two EDSS score confirmed by valid year three data (0.14 v 0.28) or when we adjusted the results to take account of the expected proportion of apparent progressions at year two that were not subsequently confirmed at year three (0.19 v 0.28).
Some patients (not included in the ORR) had delayed responses after apparent radiographic progression.
This apparent disease progression often changes the patient's status from resectable to unresectable.
A birth cohort effect was not as apparent for progression as it was for incidence.
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