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Apparent permeability coefficient.
Apparent permeability coefficient in region 3 and region 2. Permeability (mD).
The apparent permeability coefficient was indicated by the absorption rate constant P app.
The everted gut sac studies showed that the nanoemulsion facilitated the improvement of the apparent permeability coefficient (Papp).
A corneal permeation study showed that the apparent permeability coefficient of the optimal formulation was 2.03-fold higher than that of the TET solution.
Moreover, the apparent permeability coefficient (Papp) of Cur-PMs was 3.50-fold higher than that of Cur-Sol in Caco-2 transport studies.
Similar(30)
Apparent permeability coefficients (Kp) and dose absorbed were calculated and compared.
In the Caco-2 cell monolayer model, permeability was described by P AB values (the apparent permeability coefficients from AP to BL side).
The permeability of bulk phenytoin and nanophenytoin through a buccal in vitro and ex vivo model was investigated, and the apparent permeability coefficients were determined.
Compared with the TM eye drops, the TM liposome produced a 1.93 folds increase in apparent permeability coefficients (Papp), resulting in a significant increase of the corneal penetration.
To explore the relationships between bioaccumulation and uptake in the gastro intestinal tract (GIT), experimental apparent permeability coefficients (P app) values obtained from Caco-2 cells were analysed and presented by Ralph Kühne, UFZ, Leipzig.
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