Suggestions(4)
Exact(6)
The most surprising thing, Lauzen says, is the apparent lack of change.
However, the apparent lack of change in research questions over time was more surprising, particularly in light of remaining gaps in the literature.
This apparent lack of change in the temporal gene expression profile could be due to the fact that the bacterial pre-culture, used to inoculate the reactor, was pre-incubated at pH 5.2 as well.
These data are suggestive of a nontrivial system, such that despite the apparent lack of change of TAG frequency with guanine frequency the rate of TAG codon evolution is not close to zero.
Whereas it cannot be excluded that nifedipine does not target the VEGF pathway, this apparent lack of change supports the hypothesis that VEGF signalling is impaired in SSc, but more experimental data are needed in order to determine whether the VEGF pathway is intrinsically defective.
It seems that if Bailey were completely happy with the outcome of the investigation, he would release the results, but the apparent lack of change in Bailey's university status following the December 2004 conclusion of the investigation suggests the university found nothing too damning.
Similar(54)
Despite tip pinch targeting more specifically the thenar muscles the scope for improvement is limited and may explain the apparent lack of significant change after surgery.
However, regardless of which vascular mechanisms underlie the apparent lack of haemodynamic changes, the increased stroke susceptibility following arterial occlusion in BK−/− mice, along with the aggravated cell death under IVI in hippocampal BK−/− slice cultures, suggest a primarily neuronal mechanism for the protective effect of BK channels limiting brain damage during ischemia.
However, two other key claims made by the authors the apparent lack of such changes in LMAN-to-RA synapses shown in Figure 4 and the claim that the intrinsic properties of RA neurons do not change, supported by data in Figure 5E and 5F are based on the absence of a statistically significant effect.
It added: "We are concerned by the apparent lack of commitment to change, the scale of the change required and the lack of a clear plan from the ABAE setting out how the required change can be achieved".
The apparent lack of deeper volume change prior to the 2014 eruption is viewed as consistent with the water-level observations of Koizumi et al. (2016).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com